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Moreover, when fat mass shrinks especially rapidly under GLP-1 therapy stored lipophilic (fat-soluble) toxins are released into circulation

Low electrolytes can also contribute to symptoms like: Fatigue Dizziness Headaches Muscle weakness Trouble exercising and recovering Electrolyte supplements, such as low-sugar electrolyte drink mixes, can keep your energy up and help with muscle and nerve functions, along with digestion, while weight loss is occurring

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For many patients, one treatment is enough to notice a significant change, though some choose to repeat it for an even more dramatic outcome

However, clinical translation is hindered by low oral bioavailability, limited BBB permeability, and inconsistent pharmacokinetics