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Semaglutide also slows the speed at which food leaves your stomach this causes a patient to feel fuller longer so that less food (and less calories) are consumed and more weight is lost

Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults

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This also provides additional protein, which helps address the protein gap that many tirzepatide users experience

Real-world reports show wide variability: some observational analyses note that about 5% experience sleep disturbances, while a 2025 Care Pharmacy summary found that roughly 30% of patients on Wegovy reported insomnia