Overexpression of FSP1 in GPX4 knockout cells can also significantly reduce phospholipid peroxidation products, thereby inhibiting the occurrence of ferroptosis, demonstrating that the anti-ferroptosis effect of FSP1 does not depend on the expression of GPX4
Additionally, the production of hydrogen peroxide is encouraged, aggravating the effects of oxidative stress
Other approaches exploited various lexical, semantic, and syntactic features, and integrated ensemble learning and semi-supervised learning to detect ADEs [81]
doi: 10.3389/fimmu.2026.1744308 Received 11 November 2025 Revised 04 April 2026 Accepted 13 April 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Francesco Caso, University of Naples Federico II, Italy Reviewed by Piero Ruscitti, University of LAquila, Italy Silvia Scriffignano, Fondazione Istituto G.Giglio, Italy Updates Copyright 2026 Ciancio, Maranini, Sandri, Amati, Bortoluzzi, Silvagni, Govoni and Giuggioli
The aim is to give the skin time to adjust to the regenerative signalling without overwhelming the barrier