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Description

In DIO mice, SLU-PP-332 lowers hepatic neutral-lipid staining and triglyceride content and improves plasma lipid parameters

The drug is reportedly effective for weight loss because it mimics hormones that regulate appetite and blood sugar (GLP-1 and GIP)

Start at 2 mg regardless

However, even with perfect diet compliance, the loss of GLP-1's appetite-suppressing effect typically results in some weight return because the medication addresses a fundamental metabolic imbalance rather than permanently rewiring hunger mechanisms

Orlistat improved T2DM in obese people with IGT