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These findings suggest enhanced maternal-fetal transfer and activation of one-carbon metabolism during early gestation, potentially supporting epigenetic programming and impacting fetal development outcomes

1,220 PKA, a key enzyme, phosphorylates various target proteins, affecting their activity and function, which in turn promotes insulin synthesis and secretion

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Then, after 3 hours, we found moderate lesions, and finally, after 24 hours severe lesions ( Table 1, Fig