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This may establish a positive feedback loop as iron induces senescence, senescent cells accumulate more iron, and this reinforces both the senescent state and its harmful secretions

The cell pellets were cultured in chondrogenic medium (low-glucose Dulbeccos modified Eagle medium containing 0.1 mmol/L ascorbic acid 2-phosphate, 100 nmol dexamethasone, 40 g/mL proline, 100 U/mL penicillin, 100 g/mL streptomycin, and ITS Premix

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And few are more talked about than N-acetylcysteine (NAC) and Glutathione (GSH)

& Norton, R