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METHODS SUBJECTS The Framingham Heart Study is a longitudinal population-based study in which subjects have been examined every 2 years.15 The dementia study began at examination cycles 14 to 15, when participants underwent a neuropsychological test battery (age range, 55-88 years).1 At the 20th biennial examination (1986-1988), 1921 subjects from this cohort were alive and free of dementia

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10.1016/j.freeradbiomed.2014.03.025 Free Radic