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One limitation of the feedback control system used here for potential application in biomanufacturing is its use for a natural product regulated by feedback inhibition

It is commonly discussed for soft tissue recovery, mobility, and physical resilience, but it is not a cure-all and requires careful medical evaluation

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Some real-world cohorts and long-term extension trials have reported comparable efficacy of biologic agents across BMI categories, especially when weight-based dosing regimens or dose optimization strategies were applied