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67 In contrast to SOD1, SOD2 is inducible by oxidative stress, hyperoxia, environmental pollutants such as cigarette smoke or ozone, and by inflammatory cytokines

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Sixteen 911 week-old female immunocompetent Golden Syrian hamsters (Janvier Labs, Le Genest-Saint-Isle, France) were randomized according to their weight in two groups of 7 and one group of 2, with each individual animal being considered an experimental unit