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Other studies have connected low zinc levels with low IGF-1 in both rodents and humans, even when calorie intake is adequate (5, 48, 49)
Moreover, FoxO1 at the promoter level induces expression of Hmox1 (heme oxygenase 1) thereby decreasing mitochondrial respiration and ROS formation [5]
By scavenging free radicals and reducing oxidative damage to immune cells, glutathione helps to preserve their functionality and ensure an effective immune response when faced with pathogens or other challenges
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