Restoration experiments then introduce exogenous glutathione or precursors and measure recovery of redox markers, enzyme activity, and viability parameters, establishing causal relationships between GSH levels and cellular outcomes
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This complexity is further echoed in analyses that differentiate between disease stages
This process can be complex and time-consuming
A 2024 NIH-linked review estimated the prevalence of xerostomia in people with type 2 diabetes at around 42.5% , and it noted that people with insufficient saliva face a much higher risk of cavities, gingivitis, periodontitis, and other oral infections because salivas protective functions are compromised (NIH, 2024)