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Brain Res 1752:147230 Tan CC, Zhang JG, Tan MS et al (2015) NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model [J]

Recipient mice livers were harvested at various time points to monitor transplantation and repopulation

It underscores the limitations of single-targeted treatments and highlights the urgent need for multi-target approaches, search for clinical markers to enable early diagnosis, and robust clinical trial designs

Nevertheless, we argue that a cytodegeneration of the myelinating unit may be the most proximal event, which could be potentially driven by a protein misfolding mechanism like most other neurodegenerative disorders

Here is the part most patients are not told: glutathione levels are not fixed