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Moreover, consistent with the increase in PPAR and CD36 expression 25,26 , P5 chronic treatment significantly increased the number of small adipocytes in eWAT without decreasing net body fat suggesting that the G-protein-biased agonist promotes de novo differentiation of preadipocytes which reside in the stromal vascular fraction of adipose tissue
Espiritu SMG, Liu LY, Rubanova Y, Bhandari V, Holgersen EM, Szyca LM, et al
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According to the company's website and safety disclosures, you may qualify if: Your Body Mass Index (BMI) is 30 or higher (classified as obese), OR Your BMI is 27 or higher with at least one weight-related condition such as high blood pressure, type 2 diabetes, high cholesterol, obstructive sleep apnea, or cardiovascular disease, OR Your BMI is above 25 and you may still qualify depending on your overall medical history, as determined by the licensed provider The evaluating clinician reviews your full medical history during intake and makes the final determination about whether treatment is appropriate and safe for your specific situation