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Urbina SL, Roberts MD, Kephart WC, Villa KB, Santos EN, Olivencia AM, Bennett HM, Lara MD, Foster CA, Purpura M, Jger R, Taylor LW, Wilborn CD
Novel selenoproteins identified in silico and in vivo by using a conserved RNA structural motif
et al (2015) J
Furthermore, they are easily degraded and lose pharmacological activity due to the high levels of stomach acid and pepsin
Technical difficulties in manufacturing two separate peptide drugs or engineered dual-agonist drugs of high purity, stability, and consistency needed for subcutaneous injection make the development and commercialization of dual GLP-1/amylin combination drugs a significant manufacturing challenge
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