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[26] Terns Pharmaceuticals

Diabetes Res Clin Pract 2019;157:107843.ArticlePubMed 2

Gallbladder disease (added to warning label in March 2022): This is a potentially life-threatening condition that requires surgery to treat various symptoms that may include pain, inflammation, infection and blockages

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In mice lacking Nav1.6 channels, I NaP currents are reduced by 39%, and I NaR currents are suppressed by 76%, leading to the loss of subthreshold oscillations, impedance resonance, and both spontaneous and evoked rhythmic firing (Enomoto et al., 2006, 2007)