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This signaling cascade facilitates the osteogenic differentiation and calcium deposition of VSMCs, ultimately contributing to the progression of vascular calcification [118]
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[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Farmer S.R
After treatment with IGF-1, IGF-1R levels increased in membrane fraction of all the cell lysates compared to cytosolic fractions indicating IGF-1R migration to the membrane (Fig
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