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Science 366 , 1013 (2019)

Together they compress 6-12 months of healing into 6-8 weeks for many tendon and muscle injuries

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ROS also interact with unsaturated fatty acids in phospholipids, and aldehydes such as 4-hydroxynonenal, 4-hydroxyhexanal, acrolein, and MDA are the most reactive compounds (169)

Mitochondrial glutamate is subsequently converted into alpha-ketoglutarate (-KG) by glutamate dehydrogenase 1 (GLUD1 or GDH1) or by several mitochondrial aminotransferases, including glutamic-pyruvic transaminase 2 (GPT2) and glutamic-oxaloacetic transaminase 2 (GOT2)