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EndoNTsuboiNFuruhashiKShiYDuQAbeTet alUrinary soluble CD163 level reflects glomerular inflammation in human lupus nephritis
Figure 8
In exploring adjuvant therapeutic strategies for SLE, prebiotics and their related bioactive substances have demonstrated potential therapeutic value
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GLUCURONIDATION SAFE PATHWAY (UGT1A6 enzyme) 50-60% of acetaminophen in healthy non-pregnant adults Attaches glucuronic acid to make it water-soluble for urinary excretion Safe, non-toxic pathway INCREASES during pregnancy: 6% in first trimester, rising to 19% by third trimester[] Severely underdeveloped in fetuses/newborns 2
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