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The optional sub-study is being conducted at sites with CSF sampling experience and willingness to participate

Impaired transport function and composition integrity of the brain endothelium results in BBB injury in diabetes, which is related to hyperglycemia, chronic inflammation, and oxidative stress

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Persistent hiccups are uncommon but real, with about 1 in 50 Ozempic users reporting persistent hiccups at Bolt Pharmacy, which means clinicians see a small subset that requires medication or further evaluation

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