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They can, however, be indistinguishable both clinically and histologically from the CALMs of neurofibromatosis

S5 show that GLP-1RA were associated with lower risks as compared with placebo (16% lower risk), DPP-4 inhibitors (15% lower risk) and SGLT-2 inhibitors (10% lower risk), but the difference was statistically significant as compared with placebo only

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Data availability The X-ray crystallographic coordinates for structures reported in this study have been deposited at the Cambridge Crystallographic Data Centre (CCDC), under deposition number CCDC 1570955 and CCDC1549814