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Despite these limitations, the findings support recommending GLP-1RAs to facilitate weight loss and improve outcomes in CKD patients with obesity, even in the absence of diabetes

Lancet 402(10403):693704 Sattar N, Lee MMY, Kristensen SL et al (2021) Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of randomised trials

safety depends heavily on quality and oversight