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This study aims to evaluate the pattern of vitamin B 12 deficiency in a large healthcare system and assess its impact on hospitalizations and associated diseases

However, this simplification is also their main limitationthey fail to replicate the dynamic physiological conditions in living organisms

Unfortunately, it is frequently inappropriately prescribed

Conversely, sleep deprivation skews immune balance, reducing the number and function of natural killer cells (Tune et al., 2021), and elevating circulating proinflammatory cytokines, thus mimicking an inflammaging-like profile even in younger individuals ( Sex-based differences in mitochondrial physiology add an important layer of complexity when considering mitochondrial-targeted interventions for sleep, aging, and age-related inflammation