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Vacuum attenuation method Principle: By creating a pressure difference between the inside and outside of the package through vacuuming, if there is a leakage and the gas escapes, causing a change in vacuum degree, the instrument can detect the pressure attenuation and calculate the leakage rate

Gentle Swirling, No Shaking: Once the water is in, gently swirl or roll the vial until the GLP-3 powder is completely dissolved

The potential for innovative formulations suggests a promising future for this class of drugs

Ethical declarations The clinical trial was registered with the Chinese Clinical Trial Registry (registration number: ChiCTR2100049271) on July 28, 2021

doi:10.3233/JAD-142814 PubMed: 25649658 Sun X, Deng Y, Fu X, Wang S, Duan R, Zhang Y