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These drugs can also cause bone marrow abnormalities, or may cause the platelet count to increase too much

Considerable interest exists in identifying effects of these drugs beyond glucose-lowering, possibly resulting in improved macrovascular and microvascular outcomes, including in diabetic kidney disease

These studies clearly highlight trimetazidine as an anti-inflammatory medication peripherally

Reduction of Heart Failure About half of people with heart failure have preserved ejection fraction (HFpEF), so rather than diminished pump function it is the impaired ability for the heart to relax and fill (diastolic dysfunction) that accounts for their symptoms