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In BV-2 microglia, berberine down-regulates lipopolysaccharide- or interferon--induced iNOS and cyclooxygenase-2 (COX-2) level, and inhibits inflammatory cytokines expression (for example IL-6, IL-1, TNF-) (Lu et al., 2010)
Such finding implies the androgen activation existing in prostate cancer cells could be attributed to the mitochondrial DNA mutation and aging
What it does support is something more basic: womens physiology spent decades on the sidelines of clinical research, and were still filling in the gaps
Healthy methylation and folate levels protect the DNA
Tsai, K.J
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