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As a cofactor of protein and amino acid synthesis, particularly methionine, it has a crucial biochemical reaction in fat and protein metabolism

Pernicious anemia , an autoimmune disease that destroys intrinsic factor production, prevents adequate B12 absorption regardless of dietary intake or oral supplementation attempts

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NEJM 2011;365:15971604: 10.1056/NEJMoa1105816

Keep the vial tightly closed at room temperature and away from direct light