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Open-label trial of recombinant human insulin-like growth factor 1/recombinant human insulin-like growth factor binding protein 3 in myotonic dystrophy type 1

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Conclusions Nutraceuticals represent promising strategies for preventing, delaying, and addressing premature aging of the skin, especially as women advance in years (particularly after 30 years of age, when estrogen levels begin to decline and remarkably after menopause when estrogen production ceases from the ovaries)