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Yet, recent studies revealed novel and physiological roles of SGLT2 for being widely distributed in brain, especially glutamatergic pyramidal cells in the CA1 region of the hippocampus, and other organs rather than the intestine and kidney

CaCo-2 (human colorectal adenocarcinoma cells) and Huh7.5 cells (human hepatocellular carcinoma cells) were maintained at 37 C with 5% CO 2 in DMEM containing 10% FCS, GlutaMax, 1% ( v/v ) nonessential amino acids and 100 g/mL penicillin-streptomycin

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Noyce, A

This is a perfect example of why "more" is not always "better." Balance is the key to any successful wellness routine