does glp 1 cross the blood brain barrier GLP-1 and Degenerating Brain: Exploring Mechanistic Insights and Therapeutic Potential Current understanding and controversy on

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[DOI] [PubMed] [Google Scholar] 14.Yamaguchi T, Omatsu N, Matsushita S, Osumi T

However, the potential for GLP-1R endocytosis to influence pharmacodynamics of exendin-4 has previously been modelled (Gao and Jusko, 2012), and whilst this model focussed on receptor internalisation, differences in recycling and degradation rates could plausibly be linked via similar mechanisms

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