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doi: 10.1186/s12866-017-1027-1 115 KorenO.SporA.FelinJ.FkF.StombaughJ.TremaroliV.et al (2011)
However, the net effect of simultaneous glucagon receptor agonism on hypoglycaemia risk has not yet been fully established, and the overall safety profile continues to be evaluated in ongoing trials
Diabetologia 59(7):14121421 Udell JA, Yuan Z, Rush T, Sicignano NM, Galitz M, Rosenthal N (2018) Cardiovascular outcomes and risks after initiation of a sodium glucose cotransporter 2 inhibitor: results from the EASEL population-based cohort study (Evidence for cardiovascular outcomes with sodium glucose cotransporter 2 inhibitors in the real world)
This has not improved recently, with reports of a number of DSIP development and infrastructure projects left incomplete and of low quality
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