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A notable trend observed that predominance of studies linking air pollution and semen quality originate from China, shows high industrial activity, and availability of large clinical cohorts

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So when it comes to transdermal preps, which are still systemic, so theyre being absorbed like those orals, um, but they are associated with a lower clot risk than oral estrogens, since the transdermal preps avoid that absorption in the stomach and the metabolism in the liver

Future work might explore MOTS-c for specific conditions including neurodegenerative disease, cardiovascular disease, and sarcopenia

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