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First experiment: (Ethanol study), twenty-four male C57BL/6 N mice aged 1214 weeks were purchased from NIAAA and were kept in an environment with controlled temperature (23C 1 C) and a 12-h light/12-h dark cycle

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Managing Efficacy and Side Effects Throughout the Week Because GLP-1 concentration peaks early in the week and gradually declines, many patients notice stronger appetite suppression on days 1 through 4 after injection, with a gentler effect by days 6 and 7