Age of onset: congenital or acquired Anatomic site: acral, genital, conjunctival, other Color: blue nevus Microanatomic involvement Junctional (intraepidermal only) Compound (dermal and intraepidermal) Dermal (intradermal only) Cell type Spindle and epithelioid cell nevus Pigmented spindle cell nevus Epithelioid cell nevus Balloon cell nevus Eponyms (selected examples) Unna's nevus (ordinary melanocytic nevus) Miescher's nevus (ordinary melanocytic nevus) Clark's nevus (overlaps with dysplastic nevus) Spitz's nevus (spindle and epithelioid cell nevus) Zitelli's nevus (superficial congenital nevus) Mark's nevus (superficial and deep congenital nevus) Myerson's nevus (nevus with eczematous epidermal changes) Wiesner's nevus (Spitz's nevus/tumor with loss of BAP1 nuclear labeling) Tieche's nevus (common blue nevus) Ota's nevus (nevus fuscoceruleus ophthalmomaxillaris) Ito's nevus (nevus fuscoceruleus acromiodeltoideus) Sun's nevus (nevus fuscoceruleus zygomaticus) Melanocytic nevi tend to be symmetric and have fairly sharp borders
When a person loses a significant amount of weight quickly, the skin may not have enough time to adapt and tighten, resulting in loose or sagging skin
For many women with PCOS and obesity, taking GLP-1 agonists consistently for at least 24 weeks, and losing weight as a result, has been shown to help restore regular periods
NA meetings provide community, accountability, and lived experience that no drug can replicate
APAP toxicity, whether resulting from a single overdose or repeated supratherapeutic ingestion, progresses through four phases: preclinical toxic effects (phase one), hepatic injury (phase two), hepatic failure (phase three), and recovery (phase four)
