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However, in the BIOMYCO study in Belgium, DON-15-glucuronide was the main urinary DON biomarker and was found in all urine samples from the 239 adults and 155 children, within the ng/mL range (Heyndrickx et al

4.2 Oxidative stress and mitochondrial dysfunction Renal energy metabolism depends heavily on oxidative phosphorylation, and in CKD, mitochondrial dysfunction and oxidative stress form a vicious cycle that exacerbates tissue injury

Statements Author contributions ZH: Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing original draft, Writing review & editing

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Long hours, high cognitive demand and chronic background stress drive oxidative load