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Glp1r fl/fl mice treated with mGIPR-Ab/P1 also had lower total fat and inguinal WAT weights compared to vehicle, whereas Glp1r Wnt1/ mice treated with mGIPR-Ab/P1 showed no significant differences (Fig

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In another trial of liraglutide treatment for adolescents aged 1217 years, 88.8% of treated adolescents experienced adverse events, with 64.8% reporting nausea, vomiting, or diarrhea (compared to 36.5% of adolescents in the placebo group, where 84.9% experienced adverse events) (35)

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