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Girelli D, Martinelli N, Pizzolo F, Friso S, Olivieri O, Stranieri C, Trabetti E, Faccini G, Tinazzi E, Pignatti PF, Corrocher R (2003) The Interaction between MTHFR 677 CT genotype and folate status is a determinant of coronary atherosclerosis risk

Observed effects in experimental models include: Transient fatigue or lethargy following administration in animal models

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Establishing a multi-dimensional biomarker system encompassing ferroptosis-related molecules, TME-immune indicators, and non-coding RNA signatures will enable precise patient stratification

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