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This comprehensive immune response should be exploited in next-generation vaccines to complement antibodies in the global population, which is currently overwhelmingly seropositive against SARS-CoV-2 spike following vaccination and/or infection

In a high-fat diet-induced obesity mouse model, oral delivery vesicles achieve bidirectional regulation of lipid metabolism homeostasis in the liver by activating the AMPK signaling pathway in the liver

Br J Clin Pharmacol 2025 demonstrates that co-infusing a GLP-1 agonist with glucagon produces a perfectly additive HR response (+4 bpm + +4 bpm = +7 bpm at 60 min in n=12 lean males), confirming that glucagon drives chronotropy via a parallel pathway independent of GLP-1R cross-reactivity