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Dermatol Ther 35:e15656 Drishya S, Dhanisha SS, Guruvayoorappan C (2022) Antioxidant-rich fraction of Amomum subulatum fruits mitigates experimental methotrexateinduced oxidative stress by regulating TNF, IL1, and IL6 proinflammatory cytokines

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Key Highlights: Primary Endpoint Met: Orforglipron achieved superior A1C reduction vs placebo at 40 weeks: A1C reduction: 1.3% to 1.6% vs 0.1% for placebo Over 65% of patients on highest dose reached A1C 6.5% Promising Weight Loss: Patients on the highest dose experienced an average weight loss of 7.9%, with Lilly noting the effect hadnt yet plateaued

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Disturbances of mitochondrial parameters to distinguish patients with depressive episode of bipolar disorder and major depressive disorder