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[DOI] [PubMed] [Google Scholar] 13.Schaefer I.-M., Fletcher C.D

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Tirzepatide functions as a peptide hormone mimetic acting on specific cell surface receptors, while berberine operates primarily through intracellular signaling pathways and metabolic enzyme modulation

Reactive oxygen species (ROS) may directly alter vascular function or cause changes in vascular tone by several mechanisms including altered nitric oxide (NO) bioavailability or signaling

Semin Cell Dev Biol 116:9097