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Liang S, Gu Y

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Key mechanisms through which probiotics exert beneficial effects include the reinforcement of the intestinal epithelial barrier by stimulating mucin protein synthesis and regulating tight junction proteins such as occludin and claudin-1 (143)

Moreover, DEX treatment (0.5 g/kg/h, pumping injection, before induction of anesthesia to the end of surgery) has been reported to reduce cardiac troponin I and MDA levels and to decrease the incidence of arrhythmias in patients undergoing cardiac valve replacement [234, 235]