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This severe localized depletion allows neuroinflammation to run rampant, directly causing the severe cognitive impairment, memory loss, and neurological symptoms commonly referred to as "brain fog." Historically, medical science viewed the role of glutathione in chronic illness as a simple equation of "depletion." However, cutting-edge research has revealed a much more dynamic and complex reality

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In this case, the activation of 2AMPK by glucose mediates the activation of VMH GI neurons, as described by Murphy et al