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doi: 10.1016/j.ejogrb.2011.07.012 16 OrioFJrPalombaSCascellaTDi BiaseSMangusoFTauchmanovLet al

This D-retro-inverso configuration preserves the three-dimensional side-chain topology of the original FOXO4 sequence maintaining functional mimicry of the FOXO4 forkhead domains interaction surface with p53 while conferring exceptional proteolytic stability compared to the native L-amino acid sequence

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