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Stojkovic M, Machado SA, Stojkovic P, Zakhartchenko V, Hutzler P, Goncalves PB, Wolf E

It assists in offloading senescent cells, promotes cell survival, and stimulates repair mechanisms among all cells via high-grade autophagy, DNA repair, protections of the epigenome, methylation support, and diminished inflammation and LDL oxidation

Molecular markers and flow cytometry Human articular chondrocytes and C28/I2 cells were plated in 6well plates and cultured for 24 h prior to treatment.The cells were then stimulated with IL1 (10 ng/mL) for 2 h and subsequently incubated with graded concentrations of OSR (10, 20, or 40 M) for a further 24 h

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If one does not have sufficient selenium, then the enzyme glutathione peroxidase (GPX) cannot properly function