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Mislabeling, repurposing or unauthorized use violates regulatory requirements and can result in serious legal consequences for the institution

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Side Effect Profiles According to FDA safety information on testosterone therapy, traditional TRT can carry risks including: Cardiovascular complications in some men Testicular shrinkage and fertility issues Sleep apnea exacerbation Prostate enlargement concerns Blood clot risk elevation Peptide therapy typically presents fewer systemic risks because it works through natural pathways, though individual responses can vary

IL-18 acts in synergy with IL-12 to stimulate T cells production of IFN-, which in turn stimulates synovial macrophages to produce TNF- and IL-1, leading to joint inflammation and cartilage destruction (79)