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When to contact your GP or diabetes specialist nurse: If you've been taking expired Rybelsus and notice worsening blood glucose control If you experience unexplained symptoms such as persistent thirst, increased urination, or fatigue If you're unable to obtain a fresh supply of your medication For advice on alternative diabetes management strategies if Rybelsus is temporarily unavailable Seek urgent medical advice (call NHS 111) or emergency care (999) if you experience: Severe dehydration (extreme thirst, dry mouth, little or no urination) Confusion or drowsiness Rapid breathing Severe abdominal pain or persistent vomiting Very high blood glucose levels that don't respond to usual treatment These could be signs of severe hyperglycaemia or hyperosmolar hyperglycaemic state (HHS), which requires immediate medical attention
Individualized dosing under clinician guidance helps reduce risk and improve tolerability
GLP-1 medication use for type 2 diabetes has soared
Diabetes Care (2022) 45:157483
Lethal dose perspective For context, research indicates the lethal dose of GHK-CU in rodent models extrapolates to approximately 21,000mg for a 70kg human, roughly 330mg per kilogram of body weight
