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Although high ROS levels cause cellular damage and dysfunction, a low basal level of ROS is considered advantageous for maintaining cellular proliferation, differentiation, and survival [31, 32]

Systemic primary carnitine deficiency: an overview of clinical manifestations, diagnosis, and management, link: 41

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Its made of three amino acidsglutamine, glycine, and cysteineand can be increased through diet, supplementation, or lifestyle changes

Further, we found that NMN co-treatment with Dox did not increase cardiac dysfunction, which is in line with other recent work testing the impact of administering NAD + precursors, or inhibiting the NAD + consuming enzyme CD38 (Margier et al, 2022