Studies have compared MT-II with PT-141 and MC4R-selective agonists to dissect MC3R versus MC4R contributions to pro-sexual effects and to characterise the role of MC1R activation in modifying central sexual behaviour biology
Wang Y, Zhang H, Li X, et al
Two people can have similar amounts of muscle but very different: Strength Power Neuromuscular coordination Intramuscular fat Mitochondrial function Capillary supply Insulin sensitivity Ability to climb stairs, rise from a chair, or recover from illness Obesity can increase absolute muscle size because the muscles must move a larger body
Sarcopenia and Its Impact on Anti-obesity Drug Development Sarcopenic obesity, a condition defined by the co-existence of obesity and sarcopenia (loss of muscle mass and function) has emerged as a public health concern, particularly in the aging population
Kratz M, von Eckardstein A, Fobker M, Buyken A, Posny N, Schulte H et al (2002) The impact of dietary fat composition on serum leptin concentrations in healthy nonobese men and women