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Recombinant GSTO1 was pre-incubated with C1-27 at 400 nM, followed by a 40-fold dilution into assay buffer to a final concentration of 10 nM

doi: 10.1017/S1368980014001244, 8

I even stopped this one and went back to my other for a few weeks as a test

This allows practitioners to pinpoint the exact substances causing allergic reactions, giving patients a clear understanding of their triggers

For both ingredients, a few universal principles apply: patch test before full-face use, introduce one active at a time, avoid combining with incompatible ingredients, and stop use if you experience persistent irritation, allergic reaction, or unexpected pigmentary change