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full long-term data still emerging Not yet approved Pros and cons summarise available published data from peer-reviewed studies

Antibody formation against sermorelin was observed in some trial subjects without clear clinical consequence in short-term studies, though long-term immunogenicity data are limited

Smoke is another exogenous source of AGE and it has in fact been seen that the serum levels of AGE in smokers are significantly higher compared to non-smokers [46]