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Efficacy and safety of berberine for several cardiovascular diseases: A systematic review and meta-analysis of randomized controlled trials

LJA reports receiving grants or personal fees from Altimmune, AstraZeneca, Boehringer Ingelheim, Eli Lilly and Company, ERX, Gelesis, Intellihealth, Jamieson Wellness, Janssen, Novo Nordisk, Optum, Pfizer, Senda Biosciences, and Versanis and being a shareholder of ERX Pharmaceuticals, Gelesis, Intellihealth, and Jamieson Wellness

Both Novo Nordisk and Eli Lilly have invested heavily in expanding manufacturing infrastructure for oral GLP-1 therapies, including facilities across North Carolina, Texas, Alabama, and Puerto Rico

This class of drugs, initially a breakthrough for diabetes, has rapidly evolved into a cultural phenomenon, with patient usage soaring from 4 million in 2020 to an estimated 30 million by 2026